CLEXANE 4.000 I.E. 40mg/0,4ml Inj.-Lsg.i.e.F.-Sp. - Beipackzettel (2024)

FAQs

What is Clexane 4000 IU 40 mg 0.4 ml used for? ›

Clexane 40mg Injection (0.4ml Each) is an anticoagulant used to prevent and treat harmful blood clots. It stops the existing clots from getting any bigger and restricts the formation of any new clot.

Lie down or sit in a comfortable position and gently pinch a skin fold at the injection site between your thumb and index finger. Insert the needle into the skin fold at a 90° angle and press the plunger until all the medicine is injected. Do not let go of the skin fold while you are injecting.

Make sure you take the clexane at the same time every day. If you need to have an injection twice a day then give the first dose in the morning and second dose 12 hours later. Sit or lie in a comfortable position so you are relaxed. Make sure you can see the place you are going to inject.

Clexane is given either once or twice daily, depending on the underlying medical condition. Patients with mechanical heart valves are more likely to need an injection both morning and night.

Pharmacist Only Medicine

This product is a Healthcare Practitioner-only dispensed medicine.

Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers. Enoxaparin may cause bleeding problems.

Clexane should never be injected into muscle as bleeding into the muscle may occur. By gently pinching the skin between your fingers throughout the injection, the medicine only enters fatty tissue and not muscle.

Direct subcutaneous injection should be given into a subcutaneous tissue skinfold of the abdomen or the upper-outer aspect of the thigh. The skinfold should be held throughout the injection. After removal of the needle, do not rub the site. Rather, place firm, even pressure to the site of injection for 1-5 minutes.

Some of our patients say Clexane injections are painful. They're certainly notorious for bruising, so it's worth asking your clinic how to minimise this. Our top tip? Ice cubes, before and after you inject.

Don't put CLEXANE in the fridge or the freezer – keep it at room temperature. Don't take any of these medicines while you are using CLEXANE unless your nurse or doctor tells you to: Bear in mind that cold and cough remedies may contain these drugs. All these medicines can make you more likely to bleed.

Can you still get a blood clot while on Clexane? ›

Clexane stops unwanted blood clots from forming and can stop any blood clots that have already formed from growing bigger. Clexane does NOT break down blood clots that have already formed. Clexane acts as a roadblock, interfering with how the process of blood clotting occurs.

Read the medicine package leaflet before using this medication and ask the pharmacist in case of any doubt. Should I use Clexane 40 MG Injection empty stomach, before food or after food? This medication is advised to be consumed orally. If you take it on an empty stomach, it might upset the stomach.

Use in Renal Impairment

Since exposure of CLEXANE is significantly increased in patients with severe renal impairment (creatinine clearance <30 mL/min), a dosage adjustment is recommended for therapeutic and prophylactic dosage ranges.

What should I do if there is an air bubble in the syringe? Your CLEXANE syringe should contain an air bubble. This is normal and you do not need to do anything to remove the air bubble before you inject.

Before surgery, an INR of ≤ 1.5 is recommended. In many cases, the variability in decreasing INR over time warrants INR testing on the day before surgery. If it is elevated (usually > 1.8), there are data to suggest that the patient would benefit by receiving low-dose oral vitamin K (1-2.5 mg) for reversal.

Clexane is used to prevent clotting following hospital procedures or illness. Clexane is also used to treat deep vein thrombosis and heart problems including unstable angina and heart attack when taken with aspirin. Clexane is used to stop blood clots forming in the tubes of your kidney dialysis machine.

Clexane belongs to a group of drugs called anticoagulants. Clexane stops unwanted blood clots from forming and can stop any blood clots that have already formed from growing bigger.

The recommended dosage for treatment of established deep vein thrombosis with CLEXANE is 1.5 mg/kg body weight once daily (150 IU anti-Xa activity/kg body weight) or 1 mg/kg body weight (100 IU anti-Xa activity/kg bodyweight) twice daily subcutaneously.

Clexane is given by an injection under the skin once per day. Clexane can be used as "bridging" blood thinning (i.e. can be used to make sure your blood is thin enough to prevent blood thinning prior to the surgery but avoid you having an increased risk of blood clots if your warfarin level is too low).