Neonatal withdrawal symptoms from maternal use of drugs of addiction (2024)

ICD-10-CM Codes
P00-P96
P90-P96
P96-
2024 ICD-10-CM Diagnosis Code P96.1

Neonatal withdrawal symptoms from maternal use of drugs of addiction

2016

2017

2018

2019

2020

2021

2022

2023

2024

Billable/Specific Code

Code on Newborn Record

P96.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursem*nt purposes.
Short description: Neonatal w/drawal symp from matern use of drugs of addiction
The 2024 edition of ICD-10-CM P96.1 became effective on October 1, 2023.
This is the American ICD-10-CM version of P96.1 - other international versions of ICD-10 P96.1 may differ.

ICD-10-CM Coding Rules

P96.1 should be used on the newborn record - not on the maternal record.

Applicable To

Drug withdrawal syndrome in infant of dependent mother
Neonatal abstinence syndrome

Type 1 Excludes

Type 1 Excludes Help

A type 1 excludes note is a pure excludes. It means "not coded here". A type 1 excludes note indicates that the code excluded should never be used at the same time as P96.1. A type 1 excludes note is for used for when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

reactions and intoxications from maternal opiates and tranquilizers administered during labor and delivery (
ICD-10-CM Diagnosis Code P04.0
Newborn affected by maternal anesthesia and analgesia in pregnancy, labor and delivery
Applicable To
- Newborn affected by reactions and intoxications from maternal opiates and tranquilizers administered for procedures during pregnancy or labor and delivery
Type 2 Excludes
- newborn affected by other maternal medication (P04.1-)
P04.0)

The following code(s) above P96.1 contain annotation back-references

Annotation Back-References

In this context, annotation back-references refer to codes that contain:

Applicable To annotations, or
Code Also annotations, or
Code First annotations, or
Excludes1 annotations, or
Excludes2 annotations, or
Includes annotations, or
Note annotations, or
Use Additional annotations

that may be applicable to P96.1:

P00-P96
2024 ICD-10-CM Range P00-P96
Certain conditions originating in the perinatal period
Includes
- conditions that have their origin in the fetal or perinatal period (before birth through the first 28 days after birth) even if morbidity occurs later
Note
- Codes from this chapter are for use on newborn records only, never on maternal records
See Also
P96/P26 Laminate and Prepreg | Isola Group
Type 2 Excludes
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- tetanus neonatorum (A33)
Certain conditions originating in the perinatal period

Approximate Synonyms

Neonatal drug withdrawal syndrome, maternal drug abuse
Neonatal drug withdrawal syndrome, maternal drugs of abuse

Clinical Information

A constellation of signs and symptoms observable in a neonate that are consistent with maternal substance abuse or withdrawal while pregnant.
Fetal and neonatal addiction and withdrawal as a result of the mother's dependence on drugs during pregnancy. Withdrawal or abstinence symptoms develop shortly after birth. Symptoms exhibited are loud, high-pitched crying, sweating, yawning and gastrointestinal disturbances.

ICD-10-CM P96.1 is grouped within Diagnostic Related Group(s) (MS-DRG v41.0):

791 Prematurity with major problems
793 Full term neonate with major problems

Convert P96.1 to ICD-9-CM

Code History

2016 (effective 10/1/2015): New code (first year of non-draft ICD-10-CM)
2017 (effective 10/1/2016): No change
2018 (effective 10/1/2017): No change
2019 (effective 10/1/2018): No change
2020 (effective 10/1/2019): No change
2021 (effective 10/1/2020): No change
2022 (effective 10/1/2021): No change
2023 (effective 10/1/2022): No change
2024 (effective 10/1/2023): No change

Code annotations containing back-references to P96.1:

Code First: P04.1
ICD-10-CM Diagnosis Code P04.1
Newborn affected by other maternal medication
Code First
- , if applicable, withdrawal symptoms from maternal use of drugs of addiction (P96.1)
- withdrawal symptoms from therapeutic use of drugs in newborn (P96.2)
Type 1 Excludes
- dysmorphism due to warfarin (Q86.2)
- fetal hydantoin syndrome (Q86.1)
Type 2 Excludes
- maternal anesthesia and analgesia in pregnancy, labor and delivery (P04.0)
- maternal use of drugs of addiction (P04.4-)
Type 1 Excludes: P93
ICD-10-CM Diagnosis Code P93
Reactions and intoxications due to drugs administered to newborn
Includes
- reactions and intoxications due to drugs administered to fetus affecting newborn
Type 1 Excludes
- jaundice due to drugs or toxins transmitted from mother or given to newborn (P58.4-)
- reactions and intoxications from maternal opiates, tranquilizers and other medication (P04.0-P04.1, P04.4-)
- withdrawal symptoms from maternal use of drugs of addiction (P96.1)
- withdrawal symptoms from therapeutic use of drugs in newborn (P96.2)
Type 2 Excludes: P04.49
ICD-10-CM Diagnosis Code P04.49
Newborn affected by maternal use of other drugs of addiction
Type 2 Excludes
- newborn affected by maternal anesthesia and analgesia (P04.0)
- withdrawal symptoms from maternal use of drugs of addiction (P96.1)

Diagnosis Index entries containing back-references to P96.1:

Abstinence symptoms, syndrome
- neonatal P96.1
Dependence (on) (syndrome) F19.20
ICD-10-CM Diagnosis Code F19.20
Other psychoactive substance dependence, uncomplicated
Applicable To
Other (or unknown) substance use disorder, moderate
Other (or unknown) substance use disorder, severe
- drug NEC F19.20
  ICD-10-CM Diagnosis Code F19.20
  Other psychoactive substance dependence, uncomplicated
  2016 2017 2018 2019 2020 2021 2022 2023 2024 Billable/Specific Code
  Applicable To
  Other (or unknown) substance use disorder, moderate
  Other (or unknown) substance use disorder, severe
  - cocaine F14.20
    ICD-10-CM Diagnosis Code F14.20
    Cocaine dependence, uncomplicated
    2016 2017 2018 2019 2020 2021 2022 2023 2024 Billable/Specific Code
    Applicable To
    Cocaine use disorder, moderate
    Cocaine use disorder, severe
    - withdrawal symptoms in newborn P96.1
Newborn (infant) (liveborn) (singleton) Z38.2
ICD-10-CM Diagnosis Code Z38.2
Single liveborn infant, unspecified as to place of birth
Applicable To
Single liveborn infant NOS
- affected by
  - neonatal abstinence syndrome P96.1
- abstinence syndrome P96.1
Reaction - see also Disorder
- drug NEC T88.7
  ICD-10-CM Diagnosis Code T88.7
  Unspecified adverse effect of drug or medicament
  2016 2017 2018 2019 2020 2021 2022 2023 2024 Non-Billable/Non-Specific Code
  Applicable To
  Drug hypersensitivity NOS
  Drug reaction NOS
  Type 1 Excludes
  specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)
  Use Additional
  code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  - withdrawal - see Dependence, by drug, with, withdrawal
    - infant of dependent mother P96.1
    - newborn P96.1
Syndrome - see also Disease
- withdrawal - see Withdrawal, state
  - drug
    - infant of dependent mother P96.1
- abstinence, neonatal P96.1
- drug withdrawal, infant of dependent mother P96.1
- neonatal abstinence P96.1
Withdrawal state - see also Dependence, drug by type, with withdrawal
- newborn
  - infant of dependent mother P96.1

ICD-10-CM Codes Adjacent To P96.1

P93.8 Other reactions and intoxications due to drugs administered to newborn

P94 Disorders of muscle tone of newborn

P94.0 Transient neonatal myasthenia gravis

P94.1 Congenital hypertonia

P94.2 Congenital hypotonia

P94.8 Other disorders of muscle tone of newborn

P94.9 Disorder of muscle tone of newborn, unspecified

P95 Stillbirth

P96 Other conditions originating in the perinatal period

P96.0 Congenital renal failure

P96.1 Neonatal withdrawal symptoms from maternal use of drugs of addiction

P96.2 Withdrawal symptoms from therapeutic use of drugs in newborn

P96.3 Wide cranial sutures of newborn

P96.5 Complication to newborn due to (fetal) intrauterine procedure

P96.8 Other specified conditions originating in the perinatal period

P96.81 Exposure to (parental) (environmental) tobacco smoke in the perinatal period

P96.82 Delayed separation of umbilical cord

P96.83 Meconium staining

P96.89 Other specified conditions originating in the perinatal period

P96.9 Condition originating in the perinatal period, unspecified

Q00 Anencephaly and similar malformations

Reimbursem*nt claims with a date of service on or after October 1, 2015 require the use of ICD-10-CM codes.

FAQs

Neonatal withdrawal symptoms from maternal use of drugs of addiction? ›

Neonatal abstinence syndrome (NAS) is a spectrum of clinical manifestations seen in neonates due to withdrawal secondary to intrauterine drug exposure. It is most commonly associated with maternal opioid use and can be complicated by intrauterine exposure to benzodiazepines, alcohol, and various other drugs.

What is drug withdrawal syndrome in neonate of dependent mother? ›

How newborns are affected by maternal use of other drugs of addiction? ›

Babies born to substance-using mothers may have short- or long-term effects. Short-term withdrawal symptoms may consist only of mild fussiness. More severe symptoms may include irritable or jittery behavior, feeding problems, and diarrhea. Symptoms vary depending on which substances were used.

Get More Info ›

When a newborn goes through withdrawal because their mother was a frequent drug user during pregnancy? ›

Neonatal abstinence syndrome happens when babies are exposed to drugs in the womb before birth. Babies can then be affected or go through drug withdrawal after birth. Symptoms of withdrawal may begin as soon as 24 to 48 hours after birth. Or they may start as late as 5 to 10 days after birth.

Show Me More ›

What are the symptoms of neonatal abstinence syndrome in nursing? ›

One of the most apparent clusters of symptoms is neurologic excitability. A baby experiencing withdrawal may exhibit tremors in their arms or legs, which may be seen after disturbing the infant or even while they appear to be sleeping. Another symptom is irritability; the baby may cry intensely for excessive time.

See Details ›

What are signs of withdrawals in neonates? ›

Signs may include: Body shakes (tremors), seizures (convulsions), overactive reflexes (twitching) and tight muscle tone. Fussiness, excessive crying or having a high-pitched cry. Poor feeding or sucking or slow weight gain.

View Details ›

What happens if you give birth to a drug addicted baby? ›

Drug use may also result in the baby being born dependent on drugs and having to suffer withdrawal upon birth. Babies who were regularly exposed to opioids in utero may develop neonatal abstinence syndrome (NAS), a collection of problems that happens because the baby is undergoing opioid withdrawal after birth.

Explore More ›

How does a mother using drugs affect an unborn baby? ›

Babies born to moms who use drugs often have problems later in life, including: Learning and behavior problems. Slower-than-normal growth. Sudden infant death syndrome (also called SIDS).

Tell Me More ›

What drugs cause neonatal abstinence syndrome? ›

Withdrawal symptoms also may occur in babies exposed to alcohol, benzodiazepines, barbiturates, and certain antidepressants (SSRIs) while in the womb. Babies of mothers who use opioids and other addictive drugs (nicotine, amphetamines, cocaine, marijuana, alcohol) may have long-term problems.

Get More Info Here ›

How are newborns affected by maternal use of opiates? ›

Neonatal Abstinence Syndrome (NAS) – Intrauterine exposure to opioids, antidepressants, barbiturates, or benzodiazepines may result in a neonatal condition known as Neonatal Abstinence Syndrome. Infants with NAS are often fussy and hard to soothe.

What is neonatal opioid withdrawal syndrome? ›

Neonatal abstinence syndrome affects newborns whose birthing parent took or has an addiction to opioid drugs or addictive substances during pregnancy. Drug addiction is a common condition that affects an estimated 20 million people in the United States.

Get More Info ›

Which symptoms of withdrawal would the nurse expect to observe in a newborn with utero drug exposure? ›

Opioid withdrawal in a newborn causes central nervous system excitability or hyperirritability, such as tremors, stiff or rigid muscle tone, and vasomotor signs, as well as gastrointestinal signs, including vomiting and loose stools.

Get More Info ›

What birth defects are caused by drugs? ›

Some of the most severe birth defects linked to medications may include:

Cleft lips and palates.
Heart defects.
Genital defects.
Spina bifida.
Brain damage.
Glaucoma.
Abdominal trauma.
Deformed limbs.

More items...

Jan 26, 2022

View Details ›

What are the long term effects of a baby born on methadone? ›

The neurological evaluations, summarized in table 2, showed a significantly higher incidence of abnormalities in the methadone children. These abnormalities included hypotonia or hypertonia, poor fine motor coordination, delays in attaining developmental milestones, and poor language development.

Neonatal withdrawal symptoms from maternal use of drugs of addiction (2024)

Neonatal withdrawal symptoms from maternal use of drugs of addiction

Newborn affected by maternal anesthesia and analgesia in pregnancy, labor and delivery

Newborn affected by other maternal medication

Reactions and intoxications due to drugs administered to newborn

Newborn affected by maternal use of other drugs of addiction

Other psychoactive substance dependence, uncomplicated

Other psychoactive substance dependence, uncomplicated

Cocaine dependence, uncomplicated

Single liveborn infant, unspecified as to place of birth

Unspecified adverse effect of drug or medicament

FAQs

Neonatal withdrawal symptoms from maternal use of drugs of addiction? ›

What is neonatal opioid withdrawal syndrome? ›